Knowledge Sharing

2011.09.13

Correlation between fertilization rate and embryo quality of donor cryopreserved sperm with conventional IVF

Annual Meeting of Taiwanese Society for Reproductive Medicine,Abstract
Correlation between fertilization rate and embryo quality of donor cryopreserved sperm with conventional IVF

HUANG JUN-JIA1 1 2, CHEN XIU-HUI 1, Zhong- Yi Chen 1, Tsung-Hsien Lee 4, HUANG LI-XIANG 1 3, Maw-Sheng Lee 1 4
1 Division of Infertility Clinic, Lee Women’s Hospital, 2 Department of Medical Laboratory Science and Biotechnology, Central Taiwan University of Science and Technology, 3 Institute of Medicine, Chung Shan Medical University, 4 Department of Obstetrics and Gynecology, Chung Shan Medical University Hospital

According to previous studies inour hospital, based on the fact that no significant differences in the fertilization rate by donated cryopreserved sperm was found between conventional IVF and ICSI, we recommended conventional insemination in clinical practice. Here carried out computer analysis of sperm characteristics (motility, VAP, VSL, ALF) and their impact on fertilization and embryo quality. The results show in a total of 109 groups of patients from 2004 to 2010, motility did not have much impact on fertilization and embryo quality was found, a better fertilization rate was found in spermswith VSL 16 ~ 20% (n = 36), while better fertilization rate and yield of embryos was found in sperms with ALF> 1.7 (n = 36).In summary, our results demonstrated donated cryopreserved sperms with higher VSL and ALH after thawing as better candidate for insemination for better fertilization rate and embryo development.