Knowledge Sharing
2011.09.13
Clinical results of single-cell polymerase chain reaction-based pre-implantation diagnosis of thalassemia genes in IVF embryos.
2011 Annual Meeting of Taiwanese Society for Reproductive Medicine, Poster
Clinical results of single-cell polymerase chain reaction-based pre-implantation diagnosis of thalassemia genes in IVF embryos.
CAO HUI-MEI*1, BAI YI-PING 1, ZHENG EN-HUI 1, CHEN QIU-PING 1, HUANG JUN-JIA 1, Zhong- Yi Chen 1, Tsung-Hsien Lee 1,2,3, Maw-Sheng Lee 1,2,3
1 Division of Infertility Clinic, Lee Women’s Hospital, 2 Institute of Medicine, Chung Shan Medical University, 3 Department of Obstetrics and Gynecology, Chung Shan Medical University
Clinical results of single-cell polymerase chain reaction-based pre-implantation diagnosis of thalassemia genes in IVF embryos.
CAO HUI-MEI*1, BAI YI-PING 1, ZHENG EN-HUI 1, CHEN QIU-PING 1, HUANG JUN-JIA 1, Zhong- Yi Chen 1, Tsung-Hsien Lee 1,2,3, Maw-Sheng Lee 1,2,3
1 Division of Infertility Clinic, Lee Women’s Hospital, 2 Institute of Medicine, Chung Shan Medical University, 3 Department of Obstetrics and Gynecology, Chung Shan Medical University
Introduction：The aim of this study is to investigate the effect of pre-implantation embryo diagnosis on the delivery of healthy fetuses for patients carrying thalassemia genes.
Methods：Pre-implantation embryos were diagnosed withsingle cell polymerase chain reaction.
RESULTS：Of the 19 patients receiving embryo transfer, 9 had successful pregnancy. Among them, 7 delivered healthy babies, the other two patients had to terminate their pregnancy.
Conclusion：Thalassemia carriers may benefit from pre-implantation diagnosis.
