Knowledge Sharing

2025.01.21

Can Adjusting Ovulation Shot Dosage Improve Egg Maturity? What To Do If Only One Egg Matures After Ovulation Shots?

Ovulation induction is an effective way to increase pregnancy chances and is commonly used in infertility treatments. The common methods of ovulation induction vary by stimulation level, including oral ovulation medications, short-acting ovulation shots, and long-acting ovulation shots.

The choice of ovulation induction method is customized based on AMH levels and individual body conditions to ensure better egg maturity and successful outcomes.

Ovulation Shot Q&A

What is the relationship between ovulation shot dosage and ovulation?

Under normal conditions, women release one mature egg per menstrual cycle. Ovulation shots help more follicles mature, increasing the number of mature eggs released and improving the chances of pregnancy.

However, higher ovulation shot dosages do not always mean better results. For women with fewer eggs, even a high dosage may not be very effective. For women with more eggs, too high a dosage could lead to ovarian hyperstimulation syndrome (OHSS), causing side effects like abdominal bloating, pain, nausea, and vomiting.

To determine the ovulation shot dosage, doctors usually check the patient's AMH levels to assess the ovarian follicle reserve. 

Learn More:Ovulation Drug: Types, Side Effects, and Guide To Inject

When Might Ovulation Shot Dosage Need to Be Increased?

  1. Older Age (Over 35 Years Old)
  2. Low Baseline Follicle Count
  3. Pituitary Gland Insufficiency

Since everyone's body responds differently to ovulation shots, the same dosage may be too low for some and too high for others. The decision to increase the dosage should always be made by a clinical doctor based on individual conditions to ensure proper egg maturity and safety.

Are Long-Acting and Short-Acting Ovulation Shot Dosages the Same? What Are the Pros and Cons?

Ovulation shots include long-acting injections, which only require two doses during the treatment, and short-acting injections, which must be administered daily. Apart from the frequency of injections, their dosages are also different.

Long-acting ovulation shots have higher dosages, making them unsuitable for all patients. In contrast, short-acting ovulation shots allow for dosage adjustments based on the patient’s condition, offering more flexibility.

Doctors usually recommend starting with short-acting ovulation shots. This approach allows for dosage adjustments during the treatment based on follicle development, leading to better egg maturity and treatment outcomes.

250211 Differences Between Short-Acting & Long-Acting Ovulation Shots

Comparing Long-Acting and Short-Acting Ovulation Shots: Key Differences, Benefits, and Drawbacks

  Long-acting injections Short-acting ovulation shots
Dosage Higher Lower
Injection Frequency Once every 7 days Once a day
Advantages • Avoids the stress of daily injections
• High convenience, ideal for busy individuals
• Reduces the risk of missing doses or dosage errors
• Suitable for most patients
• Dosage can be adjusted during the treatment based on patient follow-ups
• Provides better treatment outcomes
Disadvantages • Dosage cannot be adjusted during the treatment
• Not suitable for women with polycystic ovary syndrome (PCOS), poor ovarian function, or a history of ovarian hyperstimulation syndrome (OHSS)
• Requires daily injections at a fixed time, which is less convenient
• Daily injections may cause significant psychological stress for patients
• Regular follow-ups are needed to monitor follicle development

Learn More:Ovulation Drug: Types, Side Effects, and Guide To Inject

Is One Mature Egg Enough After Ovulation Shots?

One mature egg per cycle is relatively low. Typically, it’s recommended to undergo multiple cycles to collect more eggs and embryos, which increases the chances of pregnancy.

n addition to the number of eggs collected, the quality of the eggs is also crucial for pregnancy chances. Successful conception requires mature, high-quality eggs. Poor-quality eggs may be harder to develop into embryos that can implant, or may lead to implantation failure or miscarriage.

Women with advanced age, low AMH levels, poor response to ovulation shots, or a diagnosis of primary ovarian insufficiency (POI) typically produce fewer eggs. Even so, successfully retrieving eggs in such cases is already a positive outcome. To improve egg quality, they can consider using specific supplements commonly referred to as "Five Egg Boosters."

What to Do If You Miss an Ovulation Shot? Will It Affect Treatment Results?

You can schedule ovulation shots based on your routine, but it’s best to take them at the same time every day.
To prevent any impact on follicle growth and egg development, avoid delaying the injection by more than two hours.
If you forget to take the shot, contact your medical consultant immediately for advice on how to make up the dose. Missing an injection can seriously affect treatment results, so it's important to follow the prescribed schedule carefully.

How Lee Women’s Hospital Assesses Ovulation Induction (OI) Medications and Shots

The evaluation for treatment is based on factors like a woman's age, ovarian reserve, baseline follicle count, and body condition.
Before starting ovulation induction, doctors perform an AMH test to understand the patient’s ovarian follicle reserve. Based on whether the patient is pursuing intrauterine insemination (IUI) or in vitro fertilization (IVF), the doctor will decide whether to use oral ovulation medications, short-acting ovulation shots, or long-acting ovulation shots to enhance egg maturity.

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