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IVF implantation failure symptoms and What's next?

There is no 100% chance that in vitro fertilization (IVF) will result in a successful pregnancy. IVF failures can be caused by a variety of intricate factors, and problems with any one step can cause the process to fail. How should infertile couples take care of themselves and begin anew after going through the psychological and physical pain of IVF failure? Before beginning the IVF process, it is imperative that we comprehend the causes of IVF failure, its symptoms, and the key factors influencing the outcome of IVF implantation.

Recognizing the Symptoms of IVF Failure

1. Menstrual Cycle

The onset of the following menstrual cycle is the most straightforward indicator of IVF failure. However, misinterpretation can happen because medications used in IVF treatment can temporarily interfere with the menstrual cycle, or because psychological stress after treatment can cause menstrual delays.

2. Pregnancy Tests

It's crucial to remember that there can be false positives or false negatives with pregnancy test kits, and their quality varies.

3. Blood Test for Pregnancy

It is recommended to have β-hCG levels measured by a blood test at the hospital after two weeks of embryo implantation in order to determine the success or failure of IVF as accurately as possible.

Please be aware that there is an increased possibility of IVF failure if you stop taking your medications after a negative home pregnancy test. Hormone levels may fluctuate in the very early stages of pregnancy, making it difficult for home pregnancy test kits to detect pregnancy.

6 Common IVF Failure Reasons

Why does IVF fail? Experiencing IVF failure can be disheartening. Let's look into the factors that may influence the outcome of IVF prior to implantation:
  • Low ovarian reserve: Ovaries produce fewer eggs and harder to fertilize.
  • Poor egg quality: Inadequate egg quality and maturity that hinder the successful embryo formation.
  • Poor sperm quality: Sperm morphology, motility, penetrability, and binding capacity can all impact fertilization potential.
  • Poor embryo development: IVF success rates are greatly lowered when embryos fail to develop past the blastocyst stage, which usually occurs on the fifth day.
  • Chromosomal Abnormalities: Individuals of advanced age or those with a history of recurrent miscarriages may have chromosomal abnormalities.
  • Uterine Pathologies: Conditions within the uterine cavity can influence the success of embryo implantation.

In the IVF process, there are several factors that can influence the success of embryo implantation. Before embarking on IVF treatment, both partners should have fertility tests done prior to starting IVF treatment. The wife typically undergoes blood tests and ultrasounds to assess the ovarian egg reserve, while the husband's sperm quality, motility, and penetrability are determined through semen analysis. Some cases may involve underlying immune issues, which require further examination.

Additionally, it might be difficult to collect enough eggs during the ovulation stimulation stage if a patient doesn't respond well to medicine or if the quality of the eggs isn't good enough. Furthermore, if not enough eggs meet the necessary criteria during the egg retrieval and selection process, they might not be able to move on to the next phase of IVF.

After Failed IVF, What's Next?

Experiencing a failed IVF can be incredibly disheartening. It's more important than anything to take good care of your body and regain a positive mindset. You can take a stroll, partake in comforting pursuits, and get ready for another try.

Post-Failed IVF Care

  • Pay extra attention to personal hygiene and cleanliness in the genital area.
  • To enhance egg quality, consider adopting a Mediterranean diet and taking supplements of vitamin D3, Coenzyme Q10, DHEA, and inositol.
  • Engage in moderate exercise and maintain a regular lifestyle.

On the second or third day of your following menstrual cycle, you can visit the clinic if you plan to move forward with the next IVF cycle. It is anticipated that you will receive good news shortly if you continue to follow medical advice and make your efforts known!

Successful Story after Failed IVF attempts

Successful childbirth after 6 failed IVF attempts in HK

Despite numerous failures at other hospitals, twins were successfully delivered

Even had underwent 5 failed IVF, still can have baby.


Read more

Understanding the symptoms of embryo implantation during IVF. Does bleeding during embryo implantation indicate failure?

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IVF Success Rates by Age: Pregnancy Success Depends on Embryo Quantity


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